SEGA GENESIS/MEGA DRIVE

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 Romance of the Three Kingdoms V

 Strategy game SKOB, 1996 

 S.S. Lucifer: Man Overboard!

 Puzzle game Codemasters, 1994 

 Sagaia

 Shooting game Taito, 1991 

 Saint Sword

 Action-adventure Taito, 1991 

 Samurai Shodown

 Fighting game Saurus, 1994 

 Samurai Spirits II

 Fighting game ???, 1998 

 Sangokushi Retsuden: Ransei...

 Strategy game Sega, 1991 

 Scooby-Doo Mystery

 Adventure game Acclaim, 1995 

 Scrabble

 Board game Supervision Entertainment, 1994 

 SeaQuest DSV

 Simulation game Black Pearl Software, 1994 

 SegGala

 Shooting game Bill Eubanks, ??? 

 Sensible Soccer

 Sports game Sony Imagesoft Inc., 1993 

 Sesame Street: Counting Cafe

 Educational game Electronic Arts, 1994 

 Shadow Blasters

 Action-adventure Sage's Creation, 1990 

 Shadow Dancer: The Secret Of Shinobi

 Action game Sega, 1990 

 Shadow of the Beast

 Action-adventure Electronic Arts, 1991 

 Shadow of the Beast II

 Action-adventure Electronic Arts, 1992 

 Shadowrun

 Adventure-RPG Sega, 1994 

 Shaq Fu

 Fighting game Electronic Arts, 1994 

 Shi Jie Zhi Bang Zheng Ba Zhan

 Sports game C&E Soft, 1994 

 ShiKinJou

 Puzzle game Sunsoft, 1991 

 Shining in the Darkness

 Adventure-RPG Sega, 1991 

 Shinobi III: Return of the Ninja Master

 Action game Sega, 1993 

 Shougi no Hoshi

 Board game Home Data, 1991 

 Shove It! ...The Warehouse Game

 Puzzle game DreamWorks, 1990 

 Show do Milhao

 Quiz game Tec Toy, 2001 

 Show do Milhao volume 2

 Quiz game Tec Toy, 2001 

 Shui Hu Feng Yun Zhuan

 Action-adventure Never Ending Soft Team, 1996 

 Shui Hu Zhuan

 Adventure-RPG Chuanpu Technologies, 1996 

 Shura no Mon

 Strategy game Sega, 1992 

 Side Pocket

 Action game Data East, 1992 

 Skitchin'

 Racing game Electronic Arts, 1994 

 Slap Fight

 Shooting game Tengen Inc., 1993 

 Slaughter Sport

 Fighting game Razorsoft, 1991 

 Smash T.V.

 Shooting game Acclaim, 1992 

 Snake Rattle 'n' Roll

 Action game Sega, 1993 

 Snow Bros - Nick and Tom

 Action game Tengen Inc., 1993 

 Socket

 Action-adventure Vic Tokai, 1993 

 Sol-Deace

 Shooting game Renovation Products, 1992 

 Sonic Crackers

 Action game Sega, 1990 

 Sonic Eraser

 Action-puzzle game Sega, 1991 

 Sonic Jam 6

 Action-adventure ???, ??? 

 Sonic Spinball

 Action game Sega, 1993 

 Sonic the Hedgehog

 Action game Sega, 1991 

 Sonic the Hedgehog 2

 Action game Sega, 1992 

 Sonic the Hedgehog 3

 Action game Sega, 1994 

 Sonic & Knuckles

 Action game Sega, 1994 

 Sonic 2 & Knuckles

 Action game Sega, 1994 

 Sonic 3 & Knuckles

 Action game Sega, 1994 

 Sorcerer's Kingdom

 Adventure-RPG Treco, 1993 

 Sorcerian

 Adventure-RPG Sega, 1990 

 Soul Blade

 Fighting game ???, ??? 

 Space Harrier II

 Shooting game Sega, 1988 

 Space Invaders '90

 Shooting game Taito, 1990 

 Space Invaders '91

 Shooting game Taito, 1991 

 Sparkster: Rocket Knight Adventures 2

 Action-adventure Konami, 1994 

 Speedball 2

 Sports game Arena Entertainment, 1992 

 Spider-Man and the X-Men...

 Action-adventure Flying Edge, 1993 

 Spider-Man vs. The Kingpin

 Action-adventure Sega, 1991 

 Spider-Man: The Animated Series

 Action-adventure Acclaim, 1993 

 Spiritual Warfare

 Action-adventure Wisdom Tree, 1994 

 Spirou

 Action-adventure Infogrames, 1995 

 Splatterhouse 2

 Action-adventure Namco Ltd., 1992 

 Splatterhouse 3

 Action-adventure Namco Ltd., 1993 

 Spot Goes To Hollywood

 Action-adventure Virgin Games, 1995 

 Squirrel King

 Action-adventure Gamtece, 1996 

 Star Control

 Strategy game Accolade, 1991 

 Starflight

 Adventure-RPG Electronic Arts, 1991 

 Stargate

 Action-adventure Acclaim, 1994 

 Steel Talons

 Shooting game Tengen Inc., 1992 

 Stormlord

 Action-adventure Razorsoft, 1991 

 Street Fighter II

 Fighting game Capcom, 1993 

 Street Racer

 Racing game Ubisoft, 1995 

 Street Smart

 Fighting game SNK, 1991 

 Streets of Rage

 Action game Sega, 1991 

 Streets of Rage II

 Action game Sega, 1992 

 Streets of Rage III

 Action game Sega, 1994 

 Strider

 Action-adventure Sega, 1990 

 Strider Returns: Journey From Darkness

 Action-adventure U.S. Gold, 1992 

 Striker

 Sports game Sega, 1995 

 Sub-Terrania

 Action game Sega, 1993 

 Summer Challenge

 Sports game Accolade, 1993 

 Sunset Riders

 Shooting game Konami, 1992 

 Super Baseball 2020

 Sports game Electronic Arts, 1993 

 Super Battleship

 Strategy game Mindscape, 1993 

 Super Battletank

 Shooting game Absolute Entertainment, 1992 

 Super Bubble Bobble

 Action game Sega, 1990 

 Super Daisenryaku

 Strategy game Sega, 1989 

 Super Donkey Kong '99

 Action-adventure Gamtec, 1999 

 Super Fantasy Zone

 Shooting game Sega, 1992 

 Super Hydlide

 Adventure-RPG Seismic, 1989 

 Super Kick Off

 Sports game U.S. Gold, 1992 

 Super Mario World

 Action-adventure ???, 1997 

 Super Monaco GP

 Racing game Sega, 1990 

 Super Off-Road

 Racing game Virgin Games, 1993 

 Super Ping-Pong

 Action game Pure-Byte, 2003 

 Super Skidmarks

 Racing game Codemasters, 1995 

 Super Street Fighter II

 Fighting game Capcom, 1994 

 Super Thunder Blade

 Shooting game Sega, 1989 

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